Liposarcoma

Excerpt

Liposarcoma, a tumor of lipoblasts, is a rare mesenchymal neoplasm that involves deep soft tissues, including the esophagus, retroperitoneum, and popliteal fossa. The relative frequency of liposarcoma at various body sites is dependent on the tumor subtypes. For example, dedifferentiated liposarcoma is much more common in retroperitoneal locations, while myxoid liposarcoma occurs in the lower extremities. Liposarcoma is exceedingly rare in the esophagus. Esophageal liposarcoma typically behaves as a slow-growing tumor and involves the upper part of the throat. Most of them are of a well-differentiated type, confined to the esophagus with a low risk of metastasis, and have a high local recurrence rate (10%), even up to 25 years after the resection.