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Book

Neuromuscular Blockade

Danielle Cook  1 , David J. Simons  2
In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2025 Jan.
.
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Free Books & Documents
Book

Neuromuscular Blockade

Danielle Cook et al.
Free Books & Documents

Excerpt

Neuromuscular blockade is frequently used in anesthesia to facilitate endotracheal intubation, optimize surgical conditions, and assist with mechanical ventilation in patients with reduced lung compliance. Neuromuscular blocking agents (NMBAs) come in two forms: depolarizing neuromuscular blocking agents (eg, succinylcholine) and nondepolarizing neuromuscular blocking agents (eg, rocuronium, vecuronium, atracurium, cisatracurium, mivacurium). The class of NMBAs used for achieving neuromuscular blockade must be selected carefully based on patient factors, the type of procedure being performed, and clinical indication.

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Conflict of interest statement

Disclosure: Danielle Cook declares no relevant financial relationships with ineligible companies.

Disclosure: David Simons declares no relevant financial relationships with ineligible companies.

References

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    1. Ahmad M, Khan NA, Furqan A. Comparing The Functional Outcome Of Different Dose Regimes Of Succinylcholine When Used For Rapid Induction And Intubation. J Ayub Med Coll Abbottabad. 2018 Jul-Sep;30(3):401-404. - PubMed
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    1. Thilen SR, Ng IC, Cain KC, Treggiari MM, Bhananker SM. Management of rocuronium neuromuscular block using a protocol for qualitative monitoring and reversal with neostigmine. Br J Anaesth. 2018 Aug;121(2):367-377. - PubMed
    1. Evaluation of Residual Neuromuscular Block Using Train-of-Four and Double Burst Stimulation at the Index Finger: Retraction Notice. Anesth Analg. 2019 Jan;128(1):e16. - PubMed

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