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Main polyamine metabolic pathways modified from Linsalata et al. (27). The abbreviations used…
Figure 1
Main polyamine metabolic pathways modified from Linsalata et al. (27). The abbreviations used are as follows: ODC, ornithine decarboxylase; SAMDC, S-adenosylmethionine decarboxylase; SSAT, spermidine-spermine-N-acetyl transferase; PAO, polyamine oxidase; AZ, antizyme; SMO, spermine oxidase. AZ inactivates ODC, increases polyamine efflux and decreases polyamine uptake.
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