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. 2019 May;25(3):e138-e145.
doi: 10.1111/hae.13698. Epub 2019 Mar 12.

Professional functioning of young adults with congenital coagulation disorders in the Netherlands

Perrine F Limperg  1 , Heleen Maurice-Stam  1 , Lotte Haverman  1 , Michiel Coppens  2 , Marieke J H A Kruip  3 , Jeroen Eikenboom  4 , Martha A Grootenhuis  1 , Marjolein Peters  5
Affiliations

Professional functioning of young adults with congenital coagulation disorders in the Netherlands

Perrine F Limperg et al. Haemophilia. 2019 May.

Abstract

Introduction and aim: Suboptimal health-related quality of life and lowered employment rates found in a previous study in young adults (YA) with congenital coagulation disorders (CCD) in the Netherlands underline the need for more insight into professional functioning of YA with CCD and into determinants of professional functioning.

Methods: Young adults (18-30 years) with CCD participated in a cross-sectional study. Professional functioning was assessed with the Work Productivity and Activity Impairment questionnaire (WPAI). Potential determinants were assessed with the Course of Life Questionnaire (CoLQ), Pediatric Quality of Life Inventory Young Adult version (PedsQL_YA), Illness Cognition Questionnaire (ICQ) and Haemophilia Activities List (HAL). Logistic regression analyses were performed in the complete sample of YA with CCD, and in YA men with haemophilia separately, to examine determinants of WPAI outcomes.

Results: Ninety-four YA (77 men; mean age 24.1 years, SD 3.5 and 17 women; mean age 24.5 years, SD 3.8) with CCD (74% haemophilia A/B) participated. 74.5% of YA were paid employed for on average 30 hours per week. Of these, more than a quarter reported work impairment. Older age and a non-severe type of haemophilia (in the sample of YA men with haemophilia) were associated with successful (paid) employment. No variables were associated with professional functioning (expressed as Presenteeism and Overall work impairment) in patients with CCD or haemophilia.

Conclusion: Three-quarters of YA with CCD were successful in finding paid employment. Though absenteeism was low, YA with paid employment needs attention as a considerable part experienced work impairment.

Keywords: haemophilia; impairment; professional functioning; work; young adults.

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Conflict of interest statement

M. Coppens has received consultancy fees from CSL Behring, Sanofi and UniQure, research support from CSL Behring and Bayer, and is study investigator for his institution for trials sponsored by Bayer, UniQure and Sanofi. All funds were received by the institution. J. Eikenboom has received research support from CSL Behring and a fee for educational activities from Roche. M. J. H. A. Kruip received Research grants from Pfizer, Bayer, Daiici Sankyo and Boehringer Ingelheim and speaker's fee from Bayer. The other authors stated that they had no interests, which might be perceived as posing a conflict or bias.

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