The Third Era of Tissue Engineering: Reversing the Innovation Drivers

Abstract

From this perspective, we discuss the different stages of development the tissue engineering (TE) field has gone through in its relatively young history. We discuss how TE is evolving from a technology-driven, science-focused field toward a patient-driven, manufacturing-focused one where patients' needs are translated into production process requirements, and subsequently into technological and biological innovations needed to meet the regulatory and clinical demands.

Keywords: modeling; developmental engineering; enabling technologies; manufacturing; patient; quality control tools.