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Editorial
. 2019 Jun 1;76(6):571-573.
doi: 10.1001/jamapsychiatry.2018.4600.

Toward an Improved Understanding of Anhedonia

Randy P Auerbach  1   2   3 , David Pagliaccio  1   2 , Diego A Pizzagalli  4   5   6
Affiliations
Editorial

Toward an Improved Understanding of Anhedonia

Randy P Auerbach et al. JAMA Psychiatry. .
No abstract available

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Conflict of interest statement

Conflicts of Interest.

Over the past 3 years, Diego Pizzagalli has received consulting fees from Akili Interactive Labs, BlackThorn Therapeutics, Boehringer Ingelheim, Compass, and Posit Science, for activities unrelated to the current research. No other authors report any conflicts of interest.

Figures

Figure 1
Figure 1
Anhedonia Biotypes Differentially Predict Long-Term Clinical Outcomes Note. A number of complementary methods can be used to probe distinct dimensions of anhedonia, including multimodal neuroimaging (illustrated above), electrophysiology, behavioral and cognitive experiments, experience sampling, and self-report. For example, in this model study, participants endorsing elevated scores on an anhedonia self-report instrument (i.e., the enriched group) would be assessed with multimodal neuroimaging approaches that probe neural circuitry associated with core domains of anhedonia (exemplar images fMRI (anticipatory), rs-fMRI (consummatory), and diffusion MRI (learning)). Multivariate taxometric analyses would use these aggregate data to form anhedonia biotypes and determine whether these separable biotypes lead to distinct psychiatric outcomes over time.
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Comment on

References

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