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. 2019 Apr 25;380(17):1589-1591.
doi: 10.1056/NEJMp1901657. Epub 2019 Mar 13.

Hypertension Hot Potato - Anatomy of the Angiotensin-Receptor Blocker Recalls

J Brian Byrd  1 , Glenn M Chertow  1 , Vivek Bhalla  1
Affiliations

Hypertension Hot Potato - Anatomy of the Angiotensin-Receptor Blocker Recalls

J Brian Byrd et al. N Engl J Med. .
No abstract available

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Figures

timeline
timeline
Recalls of Angiotensin-Receptor Blockers. The first phase of recalls involved the genotoxic impurity NDMA (blue); the second involved NDEA (green); an additional recent recall involved NMBA (orange). Company names refer to the manufacturer and are not always the same as the distributor.
See this image and copyright information in PMC

References

    1. Clin Calc Drug Stats Database: Free U.S. outpatient drug usage statistics. (Accessed February 1, 2019, at https://clinicalc.com/DrugStats.)
    1. Muntner P, Carey RM, Gidding S, et al. Potential U.S. population impact of the 2017 ACC/AHA high blood pressure guideline. J Am Coll Cardiol 2018;71:109–18. - PubMed
    1. Lowe D The sartan contamination story. In the pipeline. Science Translational Medicine January 4, 2019. https://blogs.sciencemag.org/pipeline/archives/2019/01/04/the-sartan-con...
    1. European Medicines Agency. CHMP List of questions to be addressed by the marketing authorisation holders for valsartan containing medicinal products. 2018.
    1. Loftus P Drugmakers raise prices amid shortages, Recalls; patients and pharmacies grapple with sharply higher costs for certain generic drugs. Wall Street Journal, January 18, 2019.

MeSH terms