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Comment
. 2019 May;27(5):385-386.
doi: 10.1016/j.tim.2019.02.007. Epub 2019 Mar 11.

De novo Assembly Vastly Expands the Known Microbial Universe

Samuel S Minot  1
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De novo Assembly Vastly Expands the Known Microbial Universe

Samuel S Minot. Trends Microbiol. 2019 May.

Abstract

The study of the human microbiome relies heavily on the genomes of bacterial isolates that can be grown in culture. A recent study (Pasolli et al. Cell 2019;176:649-662) of stool microbiome samples generated over 150 000 microbial genomes without any culture, vastly expanding our knowledge of the biases in existing reference databases.

Keywords: bioinformatics; microbiome.

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