Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2019 Mar;60(3):300-304.

An atypical presentation of multi-systemic B-cell lymphoma in a horse

Albert Torrent  1 , Isabelle Kilcoyne  1 , Amanda Johnson  1 , Verena K Affolter  1 , Emily Berryhill  1 , Monica Aleman  1
Affiliations
Case Reports

An atypical presentation of multi-systemic B-cell lymphoma in a horse

Albert Torrent et al. Can Vet J. 2019 Mar.

Abstract
in English, French

This report describes an unusual presentation of multicentric B-cell lymphoma with central and peripheral nerve involvement in a horse that was presented with acute onset, severe, multiple limb lameness, and muscle atrophy. This case highlights the importance of including neoplasia in the differential list in horses presenting for severe limb lameness associated with muscle atrophy, muscle fasciculations, and weakness.

Présentation atypique d’un lymphome à cellules B multisystémique chez un cheval. Ce rapport décrit la présentation inhabituelle d’un lymphome à cellules B multicentrique avec une implication du nerf central et périphérique chez un cheval qui avait été présenté avec une boiterie aiguë et grave de plusieurs membres et de l’atrophie musculaire. Ce cas souligne l’importance d’inclure la néoplasie dans la liste des diagnostics différentiels des chevaux présentés pour une boiterie grave d’un membre associée à l’atrophie musculaire, aux fasciculations musculaires et à la faiblesse.(Traduit par Isabelle Vallières).

PubMed Disclaimer

Figures

Figure 1
Figure 1
Neoplastic lymphocytes infiltrating the dorsal nerve root at the level of the 7th cervical vertebra.
Figure 2
Figure 2
Numerous CD20 positive neoplastic B-lymphocytes surround and infiltrate the nerve root. Admixed with the tumor cell population are dispersed CD3 positive reactive T-lymphocytes.
See this image and copyright information in PMC

Similar articles

See all similar articles

References

    1. Smith MO, George LW. Localization and differentiation of neurologic diseases. In: Smith BP, editor. Large Animal Internal Medicine. 4th ed. St Louis, Missouri: Mosby Elsevier; 2009. pp. 117–146.
    1. Bruere AN, Sutton RJ, Davis GB. Observations on a case of equine lymphosarcoma. N Z Vet J. 1970;18:244–252. - PubMed
    1. Lehmbecker A, Liebing J, Barthel Y, et al. Neurolymphomatosis in three horses with multicentric T-cell-rich B-cell lymphoma. J Comp Pathol. 2014;151:181–185. - PubMed
    1. Johnson AL. Differential diagnosis of muscle tremor and paresis. In: Furr M, Reed S, editors. Equine Neurology. 2nd ed. Ames, Iowa: Blackwell; 2015. pp. 149–156.
    1. Taintor J, Schleis S. Equine lymphoma. Equine Vet Educ. 2011;23:205–213.

Publication types