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. 2019 Apr 30;23(2):143-153.
doi: 10.5935/1518-0557.20190021.

Assisted Reproductive Techniques in Latin America: The Latin American Registry, 2015

Fernando Zegers-Hochschild  1   2   3 , Juan Enrique Schwarze  1   3 , Javier Crosby  1   3 , Carolina Musri  1   3 , Maria Teresa Urbina  3   4
Affiliations

Assisted Reproductive Techniques in Latin America: The Latin American Registry, 2015

Fernando Zegers-Hochschild et al. JBRA Assist Reprod. .

Abstract

Research question: What was the utilization, effectiveness and safety of assisted reproductive technologies (ART) performed in Latin American countries during 2015, and what were the regional trends?

Design: Retrospective collection of multinational data on assisted reproduction techniques (IVF and intracytoplasmic sperm injection [ICSI], frozen embryo transfer, oocyte donation, preimplantation genetic testing and fertility preservation), from 175 institutions in 15 Latin American countries.

Results: In total, 41.25% of IVF/ICSI cycles were performed in women aged 35-39 years, and 28.35% in women aged ≥40 years. After removing freeze-all cycles, delivery rate per oocyte retrieval was 21.39% for ICSI and 24.29% for IVF. Multiple births included 19.58% twins and 0.95% triplets and higher. In oocyte donation, delivery rate per transfer was 36.77%, with a twin and triplet rate of 27.65% and 1.06%, respectively. Overall, preterm deliveries reached 17.38% in singletons, 64.94% in twins and 98.41% in triplets. Perinatal mortality in 14,936 births and 18,391 babies born was 10.5 per 1000 in singletons, 17.9 per 1000 in twins, and 57.1 per 1000 in high-order multiples. Elective single embryo transfer represented 3.11% of fresh transfers, with a 31.78% delivery rate per transfer. Elective double embryo transfer represented 23.3% of transfers, with a 37.79% delivery rate per transfer. Out of 18,391 babies born, 63.22% were singletons, 34.4% twins, and 2.38% triplets and higher.

Conclusions: Given the effect of multiple births on prematurity, morbidity and perinatal mortality, reinforcing the existing trend of reducing the number of embryos transferred remains mandatory.

Keywords: ART; assisted reproductive technologies; multiple pregnancy; outcome; registry.

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Conflict of interest statement

CONFLICT OF INTERESTS

No conflict of interest have been declared.

Figures

Figure 1
Figure 1
Delivery rate per embryo transfer in IVF/intracytoplasmic sperm injection (ICSI) and oocyte donation cycles (RLA 2015)
Figure 2
Figure 2
Cumulative delivery rate (CDR) and fresh delivery rate (FDR) per initiated cycle from 2012 to 2015, according to a woman's age
See this image and copyright information in PMC

References

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