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. 2019 Mar 15;16(6):936.
doi: 10.3390/ijerph16060936.

Predictors of Lymphoceles in Women Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection for Early Gynecologic Cancer: A Retrospective Cohort Study

Hui-Hua Chen  1 , Wan-Hua Ting  2 , Ho-Hsiung Lin  3   4 , Sheng-Mou Hsiao  5   6   7
Affiliations

Predictors of Lymphoceles in Women Who Underwent Laparotomic Retroperitoneal Lymph Node Dissection for Early Gynecologic Cancer: A Retrospective Cohort Study

Hui-Hua Chen et al. Int J Environ Res Public Health. .

Abstract

Background: Lymphoceles could represent a detrimental complication after retroperitoneal lymph node dissection. Our aim was to elucidate predictors of lymphoceles. Methods: Between 2011 and 2017, medical records of consecutive women who underwent laparotomic retroperitoneal lymph node dissection for FIGO stage I or II gynecologic cancer were reviewed. Results: A total of 204 women, including those with lymphoceles (n = 31) and symptomatic lymphoceles (n = 7), were reviewed. According to multivariable analysis, parity (odds ratio = 0.59, p = 0.003), adjuvant pelvic radiotherapy (odds ratio = 2.60, p = 0.039), and peritoneal nonclosure without pelvic drainage (odds ratio = 2.31, p = 0.048) were predictors of lymphoceles. In addition, parity (odds ratio = 0.73, p = 0.03), hypertension (odds ratio = 2.62, p = 0.02), and peritoneal partial closure with pelvic drainage (odds ratio = 0.27, p = 0.02) were predictors of complications. Conclusion: Low parity, adjuvant pelvic radiotherapy, and peritoneal nonclosure without pelvic drainage were associated with increased lymphocele formation. In addition, a lower complication rate was found in the peritoneal partial closure with pelvic drainage group; thus, peritoneal partial closure with pelvic drainage might be suggested for women who undergo laparotomic retroperitoneal lymph node dissection.

Keywords: drainage; gynecology; lymph node excision; lymphocele; peritoneum.

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Conflict of interest statement

The authors declare no conflicts of interest.

Figures

Figure 1
Figure 1
The receiver operating characteristic (ROC) curves of using parity to predict lymphoceles.
Figure 2
Figure 2
The receiver operating characteristic (ROC) curves of using parity to predict complications.
See this image and copyright information in PMC

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References

    1. Mori N. Clinical and experimental studies on the so-called lymphocyst which develops after radical hysterectomy in cancer of the uterine cervix. J. Jpn. Obstet. Gynecol. Soc. 1955;2:178–203. - PubMed
    1. Logmans A., Kruyt R.H., De Bruin H.G., Cox P.H., Pillay M., Trimbos J.B. Lymphedema and lymphoceles following lymphadenectomy may be prevented by omentoplasty: A pilot study. Gynecol. Oncol. 1999;75:323–327. doi: 10.1006/gyno.1999.5624. - DOI - PubMed
    1. Gray M.J., Plentl A.A., Taylor H.C., Jr. The lymphocyst: A complication of pelvic lymph node dissections. Am. J. Obstet. Gynecol. 1958;75:1059–1062. doi: 10.1016/0002-9378(58)90825-1. - DOI - PubMed
    1. Mann W.J., Vogel F., Patsner B., Chalas E. Management of lymphoceles after radical gynecologic surgery. Gynecol. Oncol. 1989;33:248–250. doi: 10.1016/0090-8258(89)90561-1. - DOI - PubMed
    1. Benedetti-Panici P., Maneschi F., Cutillo G., D’Andrea G., di Palumbo V.S., Conte M., Scambia G., Mancuso S. A randomized study comparing retroperitoneal drainage with no drainage after lymphadenectomy in gynecologic malignancies. Gynecol. Oncol. 1997;65:478–482. doi: 10.1006/gyno.1997.4648. - DOI - PubMed

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