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. 2019 Oct;10(4):481-487.
doi: 10.1007/s12687-019-00413-y. Epub 2019 Mar 15.

Does family communication matter? Exploring knowledge of breast cancer genetics in cancer families

Deborah O Himes  1 , Sarah H Davis  2 , Jane H Lassetter  2 , Neil E Peterson  2 , Margaret F Clayton  3 , Wendy C Birmingham  4 , Anita Y Kinney  5
Affiliations

Does family communication matter? Exploring knowledge of breast cancer genetics in cancer families

Deborah O Himes et al. J Community Genet. 2019 Oct.

Abstract

Knowledge of breast cancer genetics is critical for those at increased hereditary risk who must make decisions about breast cancer screening options. This descriptive study explored theory-based relationships among cognitive and emotional variables related to knowledge of breast cancer genetics in cancer families. Participants included first-degree relatives of women with breast cancer who had received genetic counseling and testing. Study participants themselves did not have breast cancer and had not received genetic counseling or testing. Data were collected by telephone interviews and surveys. Variables analyzed included numeracy, health literacy, cancer-related distress, age, education, and the reported amount of information shared by the participants' family members about genetic counseling. The multiple regression model explained 13.9% of variance in knowledge of breast cancer genetics (p = 0.03). Best fit of the multiple regression model included all variables except education. Reported amount of information shared was the only independently significant factor associated with knowledge (β = 0.28, p = 0.01). Participants who reported higher levels of information shared by a family member about information learned during a genetic counseling session also demonstrated increased knowledge about breast cancer genetics.

Keywords: Breast cancer; Cancer genetics; Family communication; Genetic counseling; Health literacy; Knowledge; Numeracy; Precision medicine.

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Figures

Fig. 1
Fig. 1
Reported amount of information shared
Fig. 2
Fig. 2
Final multiple regression model. Influence of cognitive, emotional, and demographic factors on knowledge of breast cancer genetics. Overall model fit: R-squared = 0.139, p < 0.05
See this image and copyright information in PMC

References

    1. Ashida S, Hadley DW, Goergen AF, Skapinsky KF, Devlin HC, Koehly LM. The importance of older family members in providing social resources and promoting cancer screening in families with a hereditary cancer syndrome. The Gerontologist. 2011;51:833–842. doi: 10.1093/geront/gnr049. - DOI - PMC - PubMed
    1. Butrick M, Kelly S, Peshkin BN, Luta G, Nusbaum R, Hooker GW, Graves K, Feeley L, Isaacs C, Valdimarsdottir HB, Jandorf L, DeMarco T, Wood M, McKinnon W, Garber J, McCormick SR, Schwartz MD. Disparities in uptake of BRCA1/2 genetic testing in a randomized trial of telephone counseling. Genet Med. 2015;17:467–475. doi: 10.1038/gim.2014.125. - DOI - PMC - PubMed
    1. Centers for Disease Control and Prevention (2015) Understanding literacy and numeracy. https://www.cdc.gov/healthliteracy/learn/understandingliteracy.html. Accessed May 18, 2018
    1. Erblich J, Brown K, Kim Y, Valdimarsdottir HB, Livingston BE, and Bovbjerg DH (2005) Development and validation of a breast cancer genetic counseling knowledge questionnaire. Patient Education and Counseling 56(2):182–191. 10.1016/j.pec.2004.02.007 - PubMed
    1. van Dooren S, Rijnsburger AJ, Seynaeve C, Duivenvoorden HJ, Essink-Bot ML, Tilanus-Linthorst MMA, de Koning HJ, Tibben A. Psychological distress in women at increased risk for breast cancer: the role of risk perception. Eur J Cancer. 2004;40:2056–2063. doi: 10.1016/j.ejca.2004.05.004. - DOI - PubMed

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