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Review
. 2019 Apr;3(4):264-273.
doi: 10.1016/S2352-4642(19)30024-0.

Transmission of CMV, HTLV-1, and HIV through breastmilk

Andrew J Prendergast  1 , Ameena E Goga  2 , Catriona Waitt  3 , Antoine Gessain  4 , Graham P Taylor  5 , Nigel Rollins  6 , Elaine J Abrams  7 , E Hermione Lyall  8 , Philippe Van de Perre  9
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Free article
Review

Transmission of CMV, HTLV-1, and HIV through breastmilk

Andrew J Prendergast et al. Lancet Child Adolesc Health. 2019 Apr.
Free article

Abstract

Breastfeeding is a crucial child survival intervention. However, the potential for transmission of viral infections from mother to child presents the dilemma of how best to interpret the benefits and risks of breastfeeding in different settings. In this Review, we compare the transmission dynamics, risk factors, and outcomes of infection with three chronic viruses transmitted through breastmilk: cytomegalovirus, human T-cell lymphotropic virus type 1, and HIV. We provide an overview of intervention approaches and discuss scientific, policy, and programming gaps in the understanding of these major global infections.

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