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. 2019 Jun 20;53(6):1900028.
doi: 10.1183/13993003.00028-2019. Print 2019 Jun.

Physical activity and quality of life in patients with pulmonary hypertension

Thomas M Cascino  1 , Vallerie V McLaughlin  2 , Caroline R Richardson  3 , Nilofar Behbahani-Nejad  4 , Victor M Moles  2 , Scott H Visovatti  2 , Elizabeth A Jackson  5
Affiliations

Physical activity and quality of life in patients with pulmonary hypertension

Thomas M Cascino et al. Eur Respir J. .
No abstract available

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Conflict of interest statement

Conflict of interest: T.M. Cascino reports grants from National Institutes of Health and from University of Michigan Frankel Cardiovascular Center, during the conduct of the study. Conflict of interest: V.V. McLaughlin reports personal fees from Actelion Pharmaceuticals US, Inc., Bayer, Gilead Sciences, Inc., Medtronic, Merck, St. Jude Medical and United Therapeutics Corporation, and grants from Actelion Pharmaceuticals US, Inc., Arena, Bayer and Sonovie (University of Michigan received research funding), all outside the submitted work. Conflict of interest: C.R. Richardson has nothing to disclose. Conflict of interest: N. Behbahani-Nejad has nothing to disclose. Conflict of interest: V.M. Moles has nothing to disclose. Conflict of interest: S.H. Visovatti has nothing to disclose. Conflict of interest: E.A. Jackson has nothing to disclose.

Figures

Figure 1.
Figure 1.
a. Scatter plot with regression line showing the relationship between 6MWD and average daily step counts. Average daily step count was significantly associated with 6MWD (R=0.63, R2=0.39, p<0.001). Model fit improved when step counts included as a second order variable (R=0.71, R2=0.51, p<0.001) (shown in figure). b. Results of the multivariable linear regressions adjusting for age and sex. HRQOL and change in HRQOL were the dependent variables with average daily step counts and change in average daily step counts the primary independent variables. Regression coefficient with standard errors in parentheses, p-value and R2 displayed for each model. The emPHasis-10 score ranges from 0 – 50 with higher scores representing worse symptom burden and QOL [12]. PROMIS results are transformed using a T-score metric with a mean of 50 and a standard deviation of 10 for the general United States population. A higher score indicates more of the domain being evaluated [13]. PROMIS = Patient-Reported Outcomes Measurement Information System.
See this image and copyright information in PMC

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