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Review
. 2019 Mar;20(2):185-190.
doi: 10.5811/westjem.2018.11.39290. Epub 2019 Feb 4.

Challenging the One-hour Sepsis Bundle

Annahieta Kalantari  1 , Salim R Rezaie  2   3
Affiliations
Review

Challenging the One-hour Sepsis Bundle

Annahieta Kalantari et al. West J Emerg Med. 2019 Mar.

Abstract

In April 2018, the Surviving Sepsis Campaign (SSC) released an updated sepsis bundle, which combines directives previously listed in the three-hour and six-hour bundles. The authors discussed the reasoning and evidence supporting these changes. However, there are data that suggest these recommendations may be contrary to the best available evidence. Our purpose here is to highlight the areas where evidence is only as strong as the methodological constructs of the research used. This article is a narrative review of the available, limited evidence on which the one-hour bundle was based.

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Conflict of interest statement

Conflicts of Interest: By the WestJEM article submission agreement, all authors are required to disclose all affiliations, funding sources and financial or management relationships that could be perceived as potential sources of bias. No author has professional or financial relationships with any companies that are relevant to this study. There are no conflicts of interest or sources of funding to declare.

References

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