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. 2018 Dec 26;6(3):ofy354.
doi: 10.1093/ofid/ofy354. eCollection 2019 Mar.

Probable Donor-Derived Human Adenovirus Type 34 Infection in 2 Kidney Transplant Recipients From the Same Donor

Matthew A Pettengill  1   2 , Tara M Babu  1 , Paritosh Prasad  1 , Sally Chuang  1 , Michael G Drage  1 , Marilyn Menegus  1 , Daryl M Lamson  3 , Xiaoyan Lu  4 , Dean Erdman  4 , Nicole Pecora  1
Affiliations

Probable Donor-Derived Human Adenovirus Type 34 Infection in 2 Kidney Transplant Recipients From the Same Donor

Matthew A Pettengill et al. Open Forum Infect Dis. .

Abstract

Human adenovirus type 34 (HAdV-34) infection is a recognized cause of transplant-associated hemorrhagic cystitis and, in rare cases, tubulointerstitial nephritis. The source of such infections is often difficult to assess, that is, whether acquired as a primary infection, exposure to a pathogen in the transplanted organ, or reactivation of an endogenous latent infection. We present here 2 cases of likely transplant-acquired HAdV-34 infection from the same organ donor, manifesting as tubulointerstitial nephritis in 1.

Keywords: HAdV-34; adenovirus; kidney transplant; tubulointerstitial nephritis.

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Figures

Figure 1.
Figure 1.
Patient 1 kidney biopsy sections stained with hematoxylin and eosin (A) or adenovirus immunohistochemistry (B).
See this image and copyright information in PMC

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