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. 2019 Apr;25(4):808-810.
doi: 10.3201/eid2504.180977.

Prolonged Shedding of Zika Virus RNA in Vaginal Secretions, Nicaragua

Prolonged Shedding of Zika Virus RNA in Vaginal Secretions, Nicaragua

Yaoska Reyes et al. Emerg Infect Dis. 2019 Apr.

Abstract

Zika virus, an arthropod-borne flavivirus pathogen in humans, is unusual because it can be sexually transmitted and can be shed for prolonged periods in semen. We report viral shedding in vaginal secretions for up to 6 months, indicating the potential for sexual and vertical transmission by infected women.

Keywords: Nicaragua; Zika virus; sexually transmitted diseases; shedding; transmission; vaginal secretions; viruses.

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References

    1. Paploski IAD, Prates APPB, Cardoso CW, Kikuti M, Silva MMO, Waller LA, et al. Time lags between exanthematous illness attributed to Zika virus, Guillain-Barré syndrome, and microcephaly, Salvador, Brazil. Emerg Infect Dis. 2016;22:1438–44. 10.3201/eid2208.160496 - DOI - PMC - PubMed
    1. Hills SL, Russell K, Hennessey M, Williams C, Oster AM, Fischer M, et al. Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission—continental United States, 2016. MMWR Morb Mortal Wkly Rep. 2016;65:215–6. 10.15585/mmwr.mm6508e2 - DOI - PubMed
    1. Brasil P, Pereira JP, Moreira ME, Ribeiro Nogueira RM, Damasceno L, Wakimoto M, et al. Zika virus infection in pregnant women in Rio de Janeiro. N Engl J Med. 2016;375:2321–34. - PMC - PubMed
    1. Paz-Bailey G, Rosenberg ES, Doyle K, Munoz-Jordan J, Santiago GA, Klein L, et al. Persistence of Zika virus in body fluids—final report. N Engl J Med. 2017;379:1234–43. 10.1056/NEJMoa1613108 - DOI - PMC - PubMed
    1. Lanciotti RS, Kosoy OL, Laven JJ, Velez JO, Lambert AJ, Johnson AJ, et al. Genetic and serologic properties of Zika virus associated with an epidemic, Yap State, Micronesia, 2007. Emerg Infect Dis. 2008;14:1232–9. 10.3201/eid1408.080287 - DOI - PMC - PubMed

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