Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Apr;20(4):609-620.
doi: 10.3348/kjr.2018.0696.

Ethanol Ablation of the Thyroid Nodules: 2018 Consensus Statement by the Korean Society of Thyroid Radiology

Soo Yeon Hahn  1 , Jung Hee Shin  2 , Dong Gyu Na  3   4 , Eun Joo Ha  5 , Hye Shin Ahn  6 , Hyun Kyung Lim  7 , Jeong Hyun Lee  8 , Jeong Seon Park  9 , Ji Hoon Kim  10 , Jin Yong Sung  11 , Joon Hyung Lee  12 , Jung Hwan Baek  8 , Jung Hyun Yoon  13 , Jung Suk Sim  14 , Kwang Hwi Lee  15 , Seon Mi Baek  16 , So Lyung Jung  17 , Yeo Koon Kim  18 , Yoon Jung Choi  19 ; Korean Society of Thyroid Radiology (KSThR); Korean Society of Radiology
Affiliations
Review

Ethanol Ablation of the Thyroid Nodules: 2018 Consensus Statement by the Korean Society of Thyroid Radiology

Soo Yeon Hahn et al. Korean J Radiol. 2019 Apr.

Abstract

Minimally invasive treatment of symptomatic thyroid nodules is now commonplace. Ethanol ablation (EA) of thyroid cystic nodules has been performed since the 1990s, but there is no global consensus or guideline. Although various limitations of EA have been described, recommendations for practical application are necessary. Therefore, the Task Force Committee of the Korean Society of Thyroid Radiology initiated the present consensus statement and here we provide recommendations for the role of EA in the management of symptomatic thyroid nodules. These recommendations are based on evidence to date from the literature and expert opinion.

Keywords: Ethanol ablation; Guidelines; Minimally invasive therapy; Thyroid; Thyroid neoplasm.

PubMed Disclaimer

Conflict of interest statement

The authors have no potential conflicts of interest to disclose.

Figures

Fig. 1
Fig. 1. EA for benign recurrent cyst in right thyroid gland.
A. 18-gauge needle inserted into center of cystic area via trans-isthmic approach route. B. After aspiration of internal fluid, ethanol was slowly injected into cystic space. EA = ethanol ablation
Fig. 2
Fig. 2. EA for recurrent papillary thyroid carcinoma in right lateral neck.
A. 23-gauge needle inserted into most peripheral portion of recurrent cancer. B. Immediately after injection of ethanol, treated area became echogenic.
See this image and copyright information in PMC

References

    1. Gharib H, Papini E. Thyroid nodules: clinical importance, assessment, and treatment. Endocrinol Metab Clin North Am. 2007;36:707–735. vi. - PubMed
    1. Durante C, Costante G, Lucisano G, Bruno R, Meringolo D, Paciaroni A, et al. The natural history of benign thyroid nodules. JAMA. 2015;313:926–935. - PubMed
    1. Haugen BR, Alexander EK, Bible KC, Doherty GM, Mandel SJ, Nikiforov YE, et al. 2015 American Thyroid Association management guidelines for adult patients with thyroid nodules and differentiated thyroid cancer: the American Thyroid Association guidelines task force on thyroid nodules and differentiated thyroid cancer. Thyroid. 2016;26:1–133. - PMC - PubMed
    1. Gharib H, Papini E, Garber JR, Duick DS, Harrell RM, Hegedüs L, et al. American Association of Clinical Endocrinologists, American College of Endocrinology, and Associazione Medici Endocrinologi medical guidelines for clinical practice for the diagnosis and management of thyroid nodules--2016 update. Endocr Pract. 2016;22:622–639. - PubMed
    1. Zelmanovitz F, Genro S, Gross JL. Suppressive therapy with levothyroxine for solitary thyroid nodules: a double-blind controlled clinical study and cumulative meta-analyses. J Clin Endocrinol Metab. 1998;83:3881–3885. - PubMed

Publication types