Use of the monodisperse Pt/Ni@rGO nanocomposite synthesized by ultrasonic hydroxide assisted reduction method in electrochemical nonenzymatic glucose detection

Abstract

An electrochemical non-enzymatic sensor was developed for the detection of glucose based on an electrode modified with monodisperse platinum-nickel nanocomposites-decorated on reduced graphene oxide (Pt/Ni@rGO) which was synthesized using a new ultrasonic hydroxide assisted reduction method. Because the nanocomposites prepared by using NaOH (OH^- ligands) are much smaller nanocomposites on the supports compared to the ones without OH^- ligands. Such a monodisperse Pt/Ni@rGO nanocomposites-based electrode exhibited a high electrochemical activity for electrocatalytic oxidation of glucose in alkaline solution. Amperometric analysis showed a glucose sensitivity of 171.92 μA/mM cm² of, the detection limit of 6.3 μM and a linear range of 0.02-5.0 mM glucose concentration. Fabricated sensor platform demonstrated long-term stability and good reproducibility, in addition to high selectivity.

Keywords: Glucose detection; Nanocomposite; Non-enzymatic sensor; OH(–) ligands; Pt/Ni@rGO.