Quantitating excess tissue sodium
- PMID: 30890651
- DOI: 10.1042/CS20190037
Quantitating excess tissue sodium
Abstract
Using changes in tissue [Na+] concentration alone as done with Na+ MRI may not accurately quantitate excess tissue Na+, particularly in cellular tissues. However, individually quantitating alterations in tissue Na+ and water content as possible with ashing studies may still accurately quantitate excess tissue Na+ in these situations. Furthermore, when tissue [Na+] exceeds plasma [Na+], excess tissue Na+ must be present.
Keywords: Extracellular Matrix; Sodium; Tonicity.
© 2019 The Author(s). Published by Portland Press Limited on behalf of the Biochemical Society.
Comment in
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Response to the letter regarding the hypothesis paper "Much ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localised oedema".Clin Sci (Lond). 2019 Mar 19;133(6):761. doi: 10.1042/CS20190154. Print 2019 Mar 29. Clin Sci (Lond). 2019. PMID: 30890653
Comment on
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Much Ado about N…atrium: modelling tissue sodium as a highly sensitive marker of subclinical and localized oedema.Clin Sci (Lond). 2018 Dec 13;132(24):2609-2613. doi: 10.1042/CS20180575. Print 2018 Dec 21. Clin Sci (Lond). 2018. PMID: 30545897 Free PMC article. Review.
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