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Case Reports
. 2019 Mar 1;5(3):271-273.
doi: 10.1016/j.jdcr.2019.01.015. eCollection 2019 Mar.

Ustekinumab-induced subacute cutaneous lupus

Emma Tierney  1 , Shivashini Kirthi  1 , Bart Ramsay  1 , Kashif Ahmad  1
Affiliations
Case Reports

Ustekinumab-induced subacute cutaneous lupus

Emma Tierney et al. JAAD Case Rep. .
No abstract available

Keywords: ANA, antinuclear antibody; DILE, drug-induced lupus erythematosus; SCLE, subacute cutaneous lupus erythematosus; SLE, systemic lupus erythematosus; TNF, tumor necrosis factor; adverse drug reaction; drug induced lupus; hydroxychloroquine; psoriasis; subacute cutaneous lupus; ustekinumab; ustekinumab induced.

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Figures

Fig 1
Fig 1
SCLE rash on patient's back after second dose of ustekinumab.
Fig 2
Fig 2
SCLE rash on patient's chest after second dose of ustekinumab.
Fig 3
Fig 3
Histology (H&E) of skin biopsy shows features of lupus erythematosus: mild hyperkeratosis, a normal granular layer, and focal interface change with necrotic keratinocytes. (Hematoxylin-eosin stain.)
Fig 4
Fig 4
Resolution of subacute cutaneous lupus erythematosus rash 10 weeks after discontinuing ustekinumab.
See this image and copyright information in PMC

References

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    1. Tarazi M., Aiempanakit K., Werth V.P. Subacute cutaneous lupus erythematosus and systemic lupus erythematosus associated with abatacept. JAAD Case Rep. 2018;4:698–700. - PMC - PubMed
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    1. Grönhagen C.M., Nyberg F. Cutaneous lupus erythematosus: an update. Indian Dermatol Online J. 2014;5:7–13. - PMC - PubMed

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