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Comparative Study
. 1986;90(1-2):173-81.
doi: 10.1007/BF01314156.

Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report

W E Beyer, R W Ruigrok, H van Driel, N Masurel
Comparative Study

Influenza virus strains with a fusion threshold of pH 5.5 or lower are inhibited by amantadine. Brief report

W E Beyer et al. Arch Virol. 1986.

Abstract

Nineteen influenza virus strains were examined for susceptibility to amantadine-HCl (AMT) and for pH-thresholds of haemagglutinin-induced haemolysis. Whereas pH-thresholds below 5.5 were not seen in AMT-resistant strains, AMT-sensitive strains showed pH-thresholds either below or above 5.5.

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