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. 2019 Mar 18:114:e180545.
doi: 10.1590/0074-02760180545.

Molecular characterisation of the emerging measles virus from Roraima state, Brazil, 2018

Cátia Alexandra Ribeiro Meneses  1 , Valdinete Alves do Nascimento  2 , Victor Costa de Souza  2 , Rodrigo Melo Maito  1 , Marconi Aragão Gomes  1 , Claudeth Rocha Santa Brígida Cunha  1 , Ilma de Aguiar Antony  1 , Maria Eliane Oliveira E Silva  1 , Daniela Palha de Souza Campos  3 , André de Lima Guerra Corado  2 , Karina Pinheiro Pessoa  2 , Dana Cristina da Silva Monteiro  2 , Osnei Okumoto  4 , Marília Coelho Cunha  5 , Flávia Caselli Pacheco  5 , Felipe Gomes Naveca  2
Affiliations

Molecular characterisation of the emerging measles virus from Roraima state, Brazil, 2018

Cátia Alexandra Ribeiro Meneses et al. Mem Inst Oswaldo Cruz. .

Abstract

Measles is a human infectious disease of global concern that is caused by the measles virus. In this study, we report the complete genome sequencing of one measles virus isolate, genotype D8, that was obtained directly from a urine sample in Boa Vista city, the capital of Roraima state in Brazil. Phylogenetic reconstruction grouped the genome described in this study with that of samples from Australia, South Korea, and Italy. To our knowledge, this is the first complete genome sequence of a wild-type measles virus reported from Latin America. Therefore, the present data strengthen the current knowledge on the molecular epidemiology of measles worldwide.

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Figures

None
Phylogenetic tree of complete measles virus genomes. A mid-rooted Bayesian tree with increasing node order was constructed with the MrBayes software (version 3.2.6) and 61 taxa (complete coding sequence and intergenic regions ranging from position 108 to 15,785 for reference sequence NC_001498.1) representing all complete measles genotype D8 genomes available in GenBank on 25 January 2019 and the sequence reported in this study. Posterior probability values of each node are shown. The clade containing the sequence described in this study is highlighted in yellow. The scale bar represents nucleotide substitutions per site.
See this image and copyright information in PMC

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