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Review
. 2019 Mar 20;11(1):15.
doi: 10.1186/s13073-019-0629-7.

Circular RNAs as promising biomarkers in cancer: detection, function, and beyond

Shengli Li  1 , Leng Han  2   3
Affiliations
Review

Circular RNAs as promising biomarkers in cancer: detection, function, and beyond

Shengli Li et al. Genome Med. .

Abstract

Circular RNAs (circRNAs) are 3'-5' covalently closed RNA rings produced from back-splicing of precursor mRNA in eukaryotes. Recent studies, using both computational and experimental approaches, have allowed advanced characterization of circRNAs, leading the research field into a new era and shedding light on the contribution of circRNAs to disease.

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The authors declare that they have no competing interests.

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