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Review
. 2019 Feb 14;7(4):663-671.
doi: 10.3889/oamjms.2019.104. eCollection 2019 Feb 28.

A Review of Pancreatic Cancer: Epidemiology, Genetics, Screening, and Management

Samuel Idachaba  1 , Oluwafemi Dada  1 , Olalekan Abimbola  1 , Olamide Olayinka  1 , Akunnaya Uma  1 , Esther Olunu  1 , Adegbenro Omotuyi John Fakoya  2
Affiliations
Review

A Review of Pancreatic Cancer: Epidemiology, Genetics, Screening, and Management

Samuel Idachaba et al. Open Access Maced J Med Sci. .

Abstract

Pancreatic cancer ranks among the causes of cancer-related deaths. The average size of pancreatic cancer during diagnosis is about 31 mm and has not changed significantly over the past 30 years. Poor early diagnosis of a tumour has been attributed to the late-presenting symptoms. Over the years, improvement in the diagnosis of pancreatic cancer has been observed, and this can be linked to advancement in imaging techniques as well as the increasing knowledge of cancer history and genetics. Magnetic Resonance Imaging, Endoscopic Ultrasound, and Computer Topography are the approved imaging modalities utilised in the diagnosing of pancreatic cancer. Over the years, the management of patients with pancreatic cancer has seen remarkable improvement as reliable techniques can now be harnessed and implemented in determining the resectability of cancer. However, only about 10% of pancreatic adenocarcinomas are resectable at the time of diagnosis and will highly benefit from a microscopic margin-negative surgical resection. Overall, the failure of early tumour identification will result in considerable morbidity and mortality.

Keywords: Diagnostic Radiology; Epidemiology; Genetics; Interventional Radiology; Pancreatic Cancer; Pancreatic Management.

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Figures

Figure 1
Figure 1
The figure showing the Incidence of pancreatic cancer around the world
Figure 2
Figure 2
New incidence of pancreatic cancer was at 12.6 per 100,000 men and women annually. The number of mortality was 10.9 per 100,000 men and women annually. These rates are age-adjusted and based on 2011-2015 incidence and mortality
Figure 3
Figure 3
Five Years Relative Survival. The figure is showing a 5-year relative survival rate about the staging of cancer. The staging is broken down into Localized, Regional, Distant and Unknown.
Figure 4
Figure 4
Percent of Case by Stage. The figure shows the staging of pancreatic cancer in the American population from 2008-2014 with all races, and both exes indicated
See this image and copyright information in PMC

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