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. 2016 Jun;11(2):207-209.
doi: 10.1016/j.jds.2015.10.003. Epub 2016 Jan 15.

Acantholytic squamous cell carcinoma of soft palate-case report and literature review

Jiun-Sheng Lin  1   2   3   1   2   4   5 , Hung-Pin Lin  3   1   2   4   5 , Chung-Ji Liu  1   2   4   5
Affiliations

Acantholytic squamous cell carcinoma of soft palate-case report and literature review

Jiun-Sheng Lin et al. J Dent Sci. 2016 Jun.
No abstract available

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Figures

Figure 1
Figure 1
Histopathologic picture of our case of acantholytic squamous cell carcinoma. Infiltrating tumor cell nests with the characteristic pseudoglandular pattern, with evidence of acantholysis is present in most of the tumor cell nests: (A) hematoxylin and eosin, 40×. A higher magnification shows pseudoglandular structure lined by dysplastic squamous cells with the acantholytic cells and keratin filled in the luminal space: (B) hematoxylin and eosin, 100×. Immunohistochemical study with CD-34 illustrates positive staining with the normal vascular structure, but not the lining of the pseudoglandular structure of the tumor cell nests, a differential diagnosis from the angiosarcoma: (C) 40×. The resected specimen revealed an ulcerative lesion 6 cm × 4 cm × 3.5 cm, which extended to the maxillary sinus and bone, the infraorbital rim, ethmoid sinus, nasal mucosa, and conchae. Unfortunately, the safe margin was close to the section surface of the tumor. (D) The submandibular gland and all of the lymph nodes were free of tumor cell invasion.
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References

    1. Lever W.F. Adenoacanthoma of sweat glands-carcinoma of sweat glands with glandular and epidermal elements; report of four cases. Arch Derm Syphilol. 1947;56:157–171. - PubMed
    1. Goldman R.L., Klein H.Z., Sung M. Adenoid squamous cell carcinoma of the oral cavity; report of the first case arising in the tongue. Arch Otolaryngol. 1977;103:496–498. - PubMed
    1. González-Vela M.C., Val-Bernal J.F., Mayorga M., Zaldumbide L., Báscones M. Adenoid squamous cell carcinoma of the larynx; an uncommon histological variant of squamous cell carcinoma. APMIS. 2006;114:470–473. - PubMed
    1. Papadopoulou E., Tosios K.I., Nikitakis N., Papadogeorgakis N., Sklavounou-Andrikopoulou A. Acantholytic squamous cell carcinoma of the gingival; report of a case and review of the literature. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2010;109:e67–71. - PubMed
    1. Takagi M., Sakota Y., Takayama S., Ishikawa G. Adenoid squamous cell carcinoma of the oral mucosa: report of two autopsy casers. Cancer. 1977;40(5):2250–2255. - PubMed

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