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Review
. 2016 Dec;11(4):349-352.
doi: 10.1016/j.jds.2016.02.002. Epub 2016 Apr 11.

Quorum quenching: Signal jamming in dental plaque biofilms

Mounika Basavaraju  1 , Vidya Sagar Sisnity  1 , Rajababu Palaparthy  1 , Pavan Kumar Addanki  1
Affiliations
Review

Quorum quenching: Signal jamming in dental plaque biofilms

Mounika Basavaraju et al. J Dent Sci. 2016 Dec.

Abstract

Quorum sensing helps bacteria to communicate with each other and in coordinating their behavior. Many diseases of humans, plants, and animals are mediated by communication called quorum sensing. Various approaches are being investigated to inhibit this communication to control the diseases caused by bacteria. Periodontal pathogens also communicate through quorum sensing and new approaches to treat periodontal disease using quorum sensing inhibition need to be explored.

Keywords: acyl homoserine lactone; biofilm; periodontitis; quorum quenching; quorum sensing.

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References

    1. Moore W.E., Moore L.V. The bacteria of periodontal diseases. Periodontol 2000. 1994;5:66–67. - PubMed
    1. Shao H., Demuth D.R. Quorum sensing regulation of biofilm growth and gene expression by oral bacteria and periodontal pathogens. Periodontol 2000. 2010;52:53–67. - PubMed
    1. Federle M.J., Bassler B.L. Interspecies communication in bacteria. J Clin Invest. 2003;112:1291–1299. - PMC - PubMed
    1. Dong Y.H., Wang L.H., Zhang L.H. Quorum quenching microbial infections: mechanisms and implications. Philos Trans R Soc Lond Biol Sci. 2007;362:1201–1211. - PMC - PubMed
    1. Frias J., Olle E., Alsina M. Periodontal pathogens produce quorum sensing signal molecules. Infect Immun. 2001;69:3431–3434. - PMC - PubMed

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