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. 2017 Dec;12(4):424-425.
doi: 10.1016/j.jds.2017.09.002. Epub 2017 Oct 27.

Eosinophilic granuloma of the mandible mimicking a periapical lesion

Ying-Shiung Kuo  1   2   1   3   2   3   1   2   3   4 , Yu-Hsueh Wu  1   3   2   3   1   2   3   4 , Andy Sun  2   3   1   2   3   4 , Chun-Pin Chiang  1   2   3   4
Affiliations

Eosinophilic granuloma of the mandible mimicking a periapical lesion

Ying-Shiung Kuo et al. J Dent Sci. 2017 Dec.
No abstract available

Keywords: Langerhans cell histiocytosis; eosinophilic granuloma; immunohistochemistry; mandible.

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Figures

Fig. 1
Fig. 1
Radiograph as well as histological and immunostained microphotographs of our case of eosinophilic granuloma. (A) The panoramic radiography showed a radiolucent lesion with an irregular border at the periapical region of the left mandibular second premolar. (B) The tumor contained mainly large, pale-staining mononuclear histiocyte-like cells with coffee-beam or indented nuclei and eosinophils arranged in a sheet pattern (Hematoxylin and eosin stain; original magnification, 20×). (C) The medium-power view showed that the pale-staining histiocyte-like Langerhans cells were S100 protein-positive (immunostain; original magnification, 10×). (D) The high-power view revealed that the superficially-located lymphocytes were S100 protein-negative, but the deeply-situated Langerhans cells were S100 protein-positive (immunostain; original magnification, 20×).
See this image and copyright information in PMC

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