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. 2018 Dec;13(4):405-407.
doi: 10.1016/j.jds.2018.09.001. Epub 2018 Sep 14.

Glandular odontogenic cyst in the anterior mandible

Affiliations

Glandular odontogenic cyst in the anterior mandible

Jang-Jaer Lee et al. J Dent Sci. 2018 Dec.
No abstract available

Keywords: CK19; Fluorescent in situ hybridization (FISH); Glandular odontogenic cyst; Mandible; Mastermind-like 2 (MAML2) gene rearrangement.

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Figures

Figure 1
Figure 1
Clinical, radiographic, histological, immunostaining, and fluorescent in situ hybridization (FISH) photographs of our glandular odontogenic cyst case. (A) Clinical photograph showed no definite swelling of the anterior mandible. (B and C) Panoramic and periapical radiographs revealed a multilocular radiolucent lesion at the anterior mandibular region from tooth 31 to tooth 44. (D) High-power view demonstrated a cystic lesion lined by non-keratinized stratified squamous epithelium of varying thickness and papillary surface. Mucin-secreting cells and microcysts were discovered in the lining epithelium (H&E stain, original magnification, 20×). (E) High-power view showed small satellite cysts with mucous cells and microcysts in the lining epithelium and a row of eosinophilic cuboidal cells on the lining epithelial surface (H&E stain, original magnification, 20×). (F) Spherical nodules were occasionally observed in the lining epithelium (arrows, H&E stain, original magnification, 20×). (G) The lining epithelium was diffusely and strongly positive for CK 19 (immunostain, original magnification, 20×). (H) The lining epithelial cells were negative for Mastermind-like 2 (MAML2) gene rearrangement detected by FISH (original magnification, 100×).

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