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Comment
. 2019 Mar 21:8:e45380.
doi: 10.7554/eLife.45380.

Why structure matters

Nick Barton  1 , Joachim Hermisson  2   3 , Magnus Nordborg  4
Affiliations
Comment

Why structure matters

Nick Barton et al. Elife. .

Abstract

Great care is needed when interpreting claims about the genetic basis of human variation based on data from genome-wide association studies.

Keywords: GWAS; evolutionary biology; genetics; genomics; human; polygenic adaptation; population genetics; population structure; quantitative genetics; selection for human height.

PubMed Disclaimer

Conflict of interest statement

NB, JH, MN No competing interests declared

Figures

Figure 1.
Figure 1.. Distribution of average male height in Europe, calculated from studies performed between 1999–2013.
In general, southern Europeans tend to be shorter than northern Europeans. Image reproduced from Grasgruber et al., 2014 (CC BY 3.0).
See this image and copyright information in PMC

Comment on

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