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. 2019 Mar;98(12):e14927.
doi: 10.1097/MD.0000000000014927.

The efficacy and safety of opening-wedge high tibial osteotomy in treating unicompartmental knee osteoarthritis: Protocol for a systematic review and meta-analysis

Si-Cong Huang  1 , Yu-Fang Chen  1 , Xue-Dong Liu  1 , Yan-Hong Han  2 , Yi-Qun Li  1
Affiliations

The efficacy and safety of opening-wedge high tibial osteotomy in treating unicompartmental knee osteoarthritis: Protocol for a systematic review and meta-analysis

Si-Cong Huang et al. Medicine (Baltimore). 2019 Mar.

Abstract

Background: High tibial osteotomy (HTO) is an effective surgical technique that can stop or inhibit the progression of unicompartmental knee osteoarthritis (KOA) to avoid or postpone the need for knee arthroplasty in patients. Whether opening-wedge high tibial osteotomy (OWHTO) is superior to closing-wedge high tibial osteotomy (CWHTO) in treating unicompartmental KOA remains controversial.

Methods: Databases (Cochrane Library, EMBASE, and PubMed) were searched from their establishment to July 1, 2018 for randomized controlled trials comparing the application of OWHTO to CWHTO in patients with unicompartmental KOA. The methodological quality of each included study was assessed according to the Cochrane Handbook for Systematic Reviews of Interventions guideline. Review Manager 5.3.5 software (Cochrane Collaboration, Oxford, UK) was used to synthesize the final results.

Results: The results will provide useful information about the effectiveness and safety of OWHTO in patients with unicompartmental KOA.

Conclusion: The findings of the study will be published in a peer-reviewed journal.

Prospero registration number: CRD4201811805.

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Conflict of interest statement

The authors have no conflicts of interest to disclose.

Figures

Figure 1
Figure 1
Flow diagram of study selection process.
See this image and copyright information in PMC

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References

    1. Fibel KH, Hillstrom HJ, Halpern BC. State-of-the-art management of knee osteoarthritis. World J Clin Cases 2015;3:89–101. - PMC - PubMed
    1. Wu L, Lin J, Jin Z, et al. Comparison of clinical and radiological outcomes between opening-wedge and closing-wedge high tibial osteotomy: a comprehensive meta-analysis. PLoS One 2017;12:e171700. - PMC - PubMed
    1. Agneskirchner JD, Hurschler C, Wrann CD, et al. The effects of valgus medial opening wedge high tibial osteotomy on articular cartilage pressure of the knee: a biomechanical study. Arthroscopy 2007;23:852–61. - PubMed
    1. Aglietti P, Buzzi R, Vena LM, et al. High tibial valgus osteotomy for medial gonarthrosis: a 10 to 21-year study. J Knee Surg 2003;16:21–6. - PubMed
    1. Choi HR, Hasegawa Y, Kondo S, et al. High tibial osteotomy for varus gonarthrosis: a 10 to 24-year follow-up study. J Orthop Sci 2001;6:493–7. - PubMed