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Comment
. 2019 Mar 20;101(6):991-993.
doi: 10.1016/j.neuron.2019.03.007.

Inflaming the Brain

Hyung Jin Ahn  1 , Sarah K Baker  2 , Erin H Norris  2 , Sidney Strickland  3
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Inflaming the Brain

Hyung Jin Ahn et al. Neuron. .
Free article

Abstract

Exactly how cerebrovascular alterations contribute to Alzheimer's disease (AD) is still unknown. Merlini et al. (2019) show that blood-derived fibrinogen leads to dendritic spine elimination and cognitive deficit via microglial CD11b/CD18. Fibrinogen may be a significant contributor to AD pathogenesis.

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