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. 2019 Oct;52(5):827-830.
doi: 10.1016/j.jmii.2019.01.002. Epub 2019 Mar 8.

The microbiological characteristics of lower respiratory tract infection in patients with neuromuscular disorders: An investigation based on a multiplex polymerase chain reaction to detect viruses and a clone library analysis of the bacterial 16S rRNA gene sequence in sputum samples

Masato Ogawa  1 , Takayuki Hoshina  2 , Kaoru Haro  1 , Tokiko Kumadaki  1 , Masahiro Ishii  1 , Yoshihisa Fujino  3 , Kazumasa Fukuda  4 , Koichi Kusuhara  1
Affiliations

The microbiological characteristics of lower respiratory tract infection in patients with neuromuscular disorders: An investigation based on a multiplex polymerase chain reaction to detect viruses and a clone library analysis of the bacterial 16S rRNA gene sequence in sputum samples

Masato Ogawa et al. J Microbiol Immunol Infect. 2019 Oct.

Abstract

We performed gene amplification methods for the detections of bacteria and viruses using sputum samples to clarify the microbiological characteristics of lower respiratory tract infection in patients with neuromuscular disorders. The tendencies of higher proportion of respiratory virus detection and lower diversity of bacteria in sputum were observed.

Keywords: 16S rRNA gene; Lower respiratory tract infection; Microbiome in respiratory tract; Neuromuscular disorders; Respiratory viruses.

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