The T-lymphocyte population in first-trimester human decidua does not express the interleukin-2 receptor
- PMID: 3089922
- PMCID: PMC1453119
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The T-lymphocyte population in first-trimester human decidua does not express the interleukin-2 receptor
Immunology.
1986 Aug.
Abstract
The expression of the IL-2 receptor by T lymphocytes in human uterine decidua has been studied with two monoclonal antibodies to the IL-2 receptor employed in immunoperoxidase labelling of serial cryostat sections. Infiltrating T lymphocytes in early pregnancy decidua do not express the IL-2 receptor. Endometrial gland epithelium in early pregnancy showed unexpected reactivity with one of the mAbs to the IL-2 receptor (Tac). Thus, despite the close proximity of fetal trophoblast, macrophages and T-lineage lymphocytes in decidua in early pregnancy, IL-2 receptor-bearing lymphocytes are completely absent.
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