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. 1986 Aug;58(4):685-7.

The T-lymphocyte population in first-trimester human decidua does not express the interleukin-2 receptor

J N Bulmer, P M Johnson

The T-lymphocyte population in first-trimester human decidua does not express the interleukin-2 receptor

J N Bulmer et al. Immunology. 1986 Aug.

Abstract

The expression of the IL-2 receptor by T lymphocytes in human uterine decidua has been studied with two monoclonal antibodies to the IL-2 receptor employed in immunoperoxidase labelling of serial cryostat sections. Infiltrating T lymphocytes in early pregnancy decidua do not express the IL-2 receptor. Endometrial gland epithelium in early pregnancy showed unexpected reactivity with one of the mAbs to the IL-2 receptor (Tac). Thus, despite the close proximity of fetal trophoblast, macrophages and T-lineage lymphocytes in decidua in early pregnancy, IL-2 receptor-bearing lymphocytes are completely absent.

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