Is the Diabetic Bladder a Neurogenic Bladder? Evidence from the Literature
- PMID: 30899338
- PMCID: PMC6424349
- DOI: 10.1007/s11884-014-0255-6
Is the Diabetic Bladder a Neurogenic Bladder? Evidence from the Literature
Abstract
Diabetes can often cause LUTS. This has been called diabetic cystopathy by many authors, but no concise grouping of symptoms for this condition has been agreed upon. The etiology of diabetic cystopathy remains unknown, but evidence from the literature strongly suggests a neurologic etiology as the primary factor, with other factors such as polyuria, damage to muscle from oxidative stress, and urothelial factors possibly contributing. Once a standard definition for diabetic cystopathy can be agreed upon, prospective, longitudinal studies will play a key role in the generation of hypotheses for the causes of diabetic cystopathy. Animal models will help test these hypotheses and possibly provide strategies for prevention.
References
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- Federation ID: IDF Diabetes Atlas, 6th edn Edited by. Brussels, Belgium: International Diabetes Federation; 2013.
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- Daneshgari F, Moore C : Diabetic uropathy. Semin Nephrol 2006, 26:182–185. - PubMed
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- Changxiao H, Zhengyong Y, Shibing Y, et al. : Clinical and urodynamic evaluation of women referred with diabetes mellitus. Int Urogynecol J 2014, 25:979–983. - PubMed
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The first prospective population-based study on the prevalence of diabetic cystopathy that included urodynamic studies. More studies like this are needed.
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- Frimodt-Moller C: Diabetic cystopathy. A review of the urodynamic and clinical features of neurogenic bladder dysfunction in diabetes mellitus. Dan Med Bull 1978, 25:49–60. - PubMed
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