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. 1986 Jun;39(6):755-61.
doi: 10.7164/antibiotics.39.755.

Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. III. Structural elucidation of plipastatins

T Nishikiori, H Naganawa, Y Muraoka, T Aoyagi, H Umezawa
Free article

Plipastatins: new inhibitors of phospholipase A2, produced by Bacillus cereus BMG302-fF67. III. Structural elucidation of plipastatins

T Nishikiori et al. J Antibiot (Tokyo). 1986 Jun.
Free article

Abstract

Plipastatins are new inhibitors of phospholipase A2 produced by Bacillus cereus BMG302-fF67. Structures of the plipastatins have been determined by UV, mass and NMR spectrometries and chemical degradation. The carboxyl group of the C-terminal L-isoleucine of plipastatinic acid has been shown to form a lactone linkage with the hydroxyl group of L-tyrosine. The total structure of plipastatins has thus been established.

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