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. 2019 Mar 1;184(Suppl 1):318-321.
doi: 10.1093/milmed/usy303.

Fast Fourier Transformation of Peripheral Venous Pressure Changes More Than Vital Signs with Hemorrhage

Patrick C Bonasso  1 , Melvin S Dassinger  1 , Brady McLaughlin  2 , Jeffrey M Burford  1 , Kevin W Sexton  3
Affiliations

Fast Fourier Transformation of Peripheral Venous Pressure Changes More Than Vital Signs with Hemorrhage

Patrick C Bonasso et al. Mil Med. .

Abstract

Vital signs are included in the determination of shock secondary to hemorrhage; however, more granular predictors are needed. We hypothesized that fast Fourier transformation (FFT) would have a greater percent change after hemorrhage than heart rate (HR) or systolic blood pressure (SBP). Using a porcine model, nine 17 kg pigs were hemorrhaged 10% of their calculated blood volume. Peripheral venous pressure waveforms, HR and SBP were collected at baseline and after 10% blood loss. FFT was performed on the peripheral venous pressure waveforms and the peak between 1 and 3 hertz (f1) corresponded to HR. To normalize values for comparison, percent change was calculated for f1, SBP, and HR. The mean percent change for f1 was an 18.8% decrease; SBP was a 3.31% decrease; and HR was a 0.95% increase. Using analysis of variance, FFT at f1 demonstrates a statistically significant greater change than HR or SBP after loss of 10% of circulating blood volume (p = 0.0023). Further work is needed to determine if this could be used in field triage to guide resuscitation.

Keywords: hemorrhage; peripheral venous pressure.

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Figures

FIGURE 1.
FIGURE 1.
Peripheral venous waveform at baseline and after 10% blood loss.
FIGURE 2.
FIGURE 2.
FFT at baseline and after 10% blood loss.
See this image and copyright information in PMC

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