Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2019 Apr:35:35-41.
doi: 10.1016/j.coviro.2019.02.009. Epub 2019 Mar 19.

The intersection of sex and gender in the treatment of influenza

Affiliations
Review

The intersection of sex and gender in the treatment of influenza

Rosemary Morgan et al. Curr Opin Virol. 2019 Apr.

Abstract

Males/men and females/women differ in the outcome of influenza A virus (IAV) infections, vaccination, and antiviral treatments. Both sex (i.e. biological factors) and gender (i.e. sociocultural factors) can impact exposure and severity of IAV infections as well as responses and outcomes of treatments for IAV. Greater consideration of the combined effects of sex and gender in epidemiological, clinical, and animal studies of influenza pathogenesis is needed.

PubMed Disclaimer

References

    1. WHO: Gender, women and health. Edited by: WHO; 2014. vol 2018.]
    1. Potluri T, Engle K, Fink AL, Vom Steeg LG, Klein SL: Sex Reporting in Preclinical Microbiological and Immunological Research. MBio 2017, 8. - PMC - PubMed
    1. vom Steeg LG, Klein SL: SeXX Matters in Infectious Disease Pathogenesis. PLoS Pathog 2016, 12:e1005374. - PMC - PubMed
    1. Peiris JS, Hui KP, Yen HL: Host response to influenza virus: protection versus immunopathology. Curr Opin Immunol 2010, 22:475–481. - PMC - PubMed
    1. Quach C, Piche-Walker L, Platt R, Moore D: Risk factors associated with severe influenza infections in childhood: implication for vaccine strategy. Pediatrics 2003, 112:e197–201. - PubMed

Publication types

Substances