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. 2019 May:160:154-156.
doi: 10.1016/j.mimet.2019.03.019. Epub 2019 Mar 20.

Detection of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae using the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay

Yasuhide Kawamoto  1 , Kosuke Kosai  2 , Hiromi Yamakawa  1 , Norihito Kaku  1 , Naoki Uno  3 , Yoshitomo Morinaga  3 , Hiroo Hasegawa  1 , Katsunori Yanagihara  4
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Detection of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae using the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay

Yasuhide Kawamoto et al. J Microbiol Methods. 2019 May.

Abstract

The MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay, which analyzes bacterial induced hydrolysis of cefotaxime using MALDI-TOF MS, correctly identified 100.0% of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae as positive and 94.7% of non-ESBL producers as negative in 80 strains tested.

Keywords: Antibiotic resistance; ESBL; MALDI-TOF MS.

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