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. 1986 May;7(5):327-36.
doi: 10.1097/00006231-198605000-00002.

The sterility testing of dispensed radiopharmaceuticals

The sterility testing of dispensed radiopharmaceuticals

S Brown et al. Nucl Med Commun. 1986 May.

Abstract

The benefits of retrospective sterility tests on radiopharmaceuticals, were assessed by following the survival of bacteria in non-radioactive and radioactive kits and generator eluate over a period of 5 days. The response of bacteria inoculated into non-radioactive materials ranged through death, survival and growth. The response of bacteria inoculated into radioactive materials was either death or survival. The value of retrospective sterility testing is doubtful and an improved test method is suggested.

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