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Review
. 2019 Mar 18:8:F1000 Faculty Rev-302.
doi: 10.12688/f1000research.16357.1. eCollection 2019.

Recent advances in spontaneous intracerebral hemorrhage

Ravi Garg  1 , José Biller  1
Affiliations
Review

Recent advances in spontaneous intracerebral hemorrhage

Ravi Garg et al. F1000Res. .

Abstract

Intracerebral hemorrhage (ICH) is a stroke subtype associated with significant morbidity and mortality. The purpose of this review is to provide an update on important research on ICH over the past three years. Topics covered include risk factors, imaging predictors of hematoma expansion, scoring schema to predict hematoma expansion, hemostatic therapies, acute blood pressure lowering, intraventricular administration of alteplase for intraventricular hemorrhage, and the current status of surgical therapies.

Keywords: antithrombotic reversal; blood pressure lowering; deompressive hemicraniectomy; hematoma expansion; intracerebral hemorrhage; intraventricular alteplase.

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Conflict of interest statement

No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.No competing interests were disclosed.

Figures

Figure 1.
Figure 1.. Intracerebral Hemorrhage due to arterial hypertension.
( A) Hyper-attenuating hemorrhage visualized in the pons. ( B) Hyper-attenuating hemorrhage centered in the left medial thalamus. Both locations are typical for hemorrhage related to long-standing hypertensive arteriopathy. These images constitute original, unpublished data obtained by the authors.
Figure 2.
Figure 2.. Left putaminal hemorrhage with positive “black hole sign”.
A well-delineated margin is appreciated between the hypo-attenuating, round black hole and the hyper-attenuating hemorrhage. This image constitutes original, unpublished data obtained by the authors.
Figure 3.
Figure 3.. Rivaroxaban-related intracerebral hemorrhage.
Hyper-attenuating hemorrhage is visualized in the left posterior temporal-parietal region with intraventricular extension. This image constitutes original, unpublished data obtained by the authors.
See this image and copyright information in PMC

References

    1. An SJ, Kim TJ, Yoon BW: Epidemiology, Risk Factors, and Clinical Features of Intracerebral Hemorrhage: An Update. J Stroke. 2017;19(1):3–10. 10.5853/jos.2016.00864 - DOI - PMC - PubMed

    2. F1000 Recommendation

    1. Muntner P, Carey RM, Gidding S, et al. : Potential US Population Impact of the 2017 ACC/AHA High Blood Pressure Guideline. Circulation. 2018;137(2):109–18. 10.1161/CIRCULATIONAHA.117.032582 - DOI - PMC - PubMed

    2. F1000 Recommendation

    1. Khan NI, Siddiqui FM, Goldstein JN, et al. : Association Between Previous Use of Antiplatelet Therapy and Intracerebral Hemorrhage Outcomes. Stroke. 2017;48(7):1810–7. 10.1161/STROKEAHA.117.016290 - DOI - PubMed

    2. F1000 Recommendation

    1. Renoux C, Vahey S, Dell’Aniello S, et al. : Association of Selective Serotonin Reuptake Inhibitors With the Risk for Spontaneous Intracranial Hemorrhage. JAMA Neurol. 2017;74(2):173–180. 10.1001/jamaneurol.2016.4529 - DOI - PubMed

    2. F1000 Recommendation

    1. Endres M, Nolte CH, Scheitz JF: Statin Treatment in Patients With Intracerebral Hemorrhage. Stroke. 2018;49(1):240–6. 10.1161/STROKEAHA.117.019322 - DOI - PubMed

    2. F1000 Recommendation