Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2019 Feb;7(3):57.
doi: 10.21037/atm.2018.12.55.

GABA strikes down again in epilepsy

Affiliations
Editorial

GABA strikes down again in epilepsy

Milena Guazzi et al. Ann Transl Med. 2019 Feb.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: P Striano has served on a scientific advisory board or received honoraria from GW pharma, Kolfarma s.r.l., and Eisai pharma; he has received research support from the Italian Ministry of Health.

Comment on

References

    1. Butler KM, Moody OA, Schuler E, et al. De novo variants in GABRA2 and GABRA5 alter receptor function and contribute to early-onset epilepsy. Brain 2018. [Epub ahead of print]. 10.1093/brain/awy171 - DOI - PMC - PubMed
    1. Kang JQ. Defects at the crossroads of GABAergic signaling in generalized genetic epilepsies. Epilepsy Res 2017;137:9-18. 10.1016/j.eplepsyres.2017.08.013 - DOI - PMC - PubMed
    1. Hirose S. Mutant GABA(A) receptor subunits in genetic (idiopathic) epilepsy. Prog Brain Res 2014;213:55-85. 10.1016/B978-0-444-63326-2.00003-X - DOI - PubMed
    1. Mefford HC. Expanding role of GABAA receptors in generalised epilepsies. Lancet Neurol 2018;17:657-8. 10.1016/S1474-4422(18)30252-7 - DOI - PubMed
    1. May P, Girard S, Harrer M, et al. Rare coding variants in genes encoding GABAA receptors in genetic generalised epilepsies: an exome-based case-control study. Lancet Neurol 2018;17:699-708. 10.1016/S1474-4422(18)30215-1 - DOI - PubMed