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Comment
. 2019 May 1;199(9):1045-1047.
doi: 10.1164/rccm.201903-0667ED.

Functional Role of Inflammasome Activation in a Subset of Obese Nonsmoking Patients with Severe Asthma

Paolo Ruggeri  1 , Gaetano Caramori  1
Affiliations
Comment

Functional Role of Inflammasome Activation in a Subset of Obese Nonsmoking Patients with Severe Asthma

Paolo Ruggeri et al. Am J Respir Crit Care Med. .
No abstract available

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Figures

Figure 1.
Figure 1.
The main stimuli involved in inflammasome activation and related intra- and extracellular functional responses. DAMPs = damage-associated molecular patterns; eATP = extracellular ATP; eDNA = extracellular DNA; HMGB-1 = high-mobility group box protein-1; NETs = neutrophil extracellular traps; NLRP3 = nucleotide-binding oligomerization domain–like receptor family, pyrin domain–containing 3; PAMPs = pathogen-associated molecular patterns.
See this image and copyright information in PMC

Comment on

  • Extracellular DNA, Neutrophil Extracellular Traps, and Inflammasome Activation in Severe Asthma.
    Lachowicz-Scroggins ME, Dunican EM, Charbit AR, Raymond W, Looney MR, Peters MC, Gordon ED, Woodruff PG, Lefrançais E, Phillips BR, Mauger DT, Comhair SA, Erzurum SC, Johansson MW, Jarjour NN, Coverstone AM, Castro M, Hastie AT, Bleecker ER, Fajt ML, Wenzel SE, Israel E, Levy BD, Fahy JV. Lachowicz-Scroggins ME, et al. Am J Respir Crit Care Med. 2019 May 1;199(9):1076-1085. doi: 10.1164/rccm.201810-1869OC. Am J Respir Crit Care Med. 2019. PMID: 30888839 Free PMC article.

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