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. 2019 Sep;139(9):2042-2045.e8.
doi: 10.1016/j.jid.2019.02.029. Epub 2019 Mar 22.

Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for Subsequent Basal Cell Carcinoma

Yadav Sapkota  1 , Lucie M Turcotte  2 , Matthew J Ehrhardt  3 , Rebecca M Howell  4 , Michael A Arnold  5 , Carmen L Wilson  6 , Wendy Leisenring  7 , Zhaoming Wang  8 , Joshua Sampson  9 , Casey L Dagnall  10 , Eric Karlins  10 , Shengchao Alfred Li  10 , Belynda D Hicks  10 , Rita Weathers  4 , Susan A Smith  4 , Kyla Shelton  6 , Qi Liu  11 , Margaret A Tucker  9 , Stephen J Chanock  9 , Jinghui Zhang  8 , Melissa M Hudson  3 , Joseph P Neglia  2 , Gregory T Armstrong  3 , Leslie L Robison  6 , Lindsay M Morton  9 , Smita Bhatia  12 , Yutaka Yasui  13
Affiliations

Genome-Wide Association Study in Irradiated Childhood Cancer Survivors Identifies HTR2A for Subsequent Basal Cell Carcinoma

Yadav Sapkota et al. J Invest Dermatol. 2019 Sep.
No abstract available

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Conflict of interest statement

CONFLICT OF INTERESTS

We declare no conflict of interests.

Figures

Figure 1 |
Figure 1 |
LocusZoom plot of the HTR2A risk locus for subsequent basal cell carcinoma (BCC). Association with the risk of subsequent BCC is expressed as −log10 (p-value) obtained from GWA analysis of autosomal SNPs in low-risk subgroup of the Childhood Cancer Survivor Study discovery cohort. Results for the SNPs within +/− 250kb of the top SNP rs633737 are shown. SNPs are shown as circles, diamonds or squares, with the top SNP represented by purple color. All other SNPs are color coded according to the strength of LD with the top SNP (as measured by r2 in the European 1000 Genomes data).
See this image and copyright information in PMC

References

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