Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 May;21(5):687-688.
doi: 10.1111/jch.13524. Epub 2019 Mar 26.

Can Aliskiren "COMPLEMENT" our management of kidney disease?

Affiliations
Comment

Can Aliskiren "COMPLEMENT" our management of kidney disease?

Sheena Pramod et al. J Clin Hypertens (Greenwich). 2019 May.
No abstract available

Keywords: Aliskiren; complement; glomerular; renin.

PubMed Disclaimer

Conflict of interest statement

None.

Comment on

References

    1. Thurman JM, Nester CM. All things complement. Clin J Am Soc Nephrol. 2016;11(10):1856‐1866. - PMC - PubMed
    1. Wood JM, Schnell CR, Cumin F, Menard J, Webb RL. Aliskiren, a novel, orally effective renin inhibitor, lowers blood pressure in marmosets and spontaneously hypertensive rats. J Hypertens. 2005;23(2):417‐426. - PubMed
    1. Kelly DJ, Zhang Y, Moe G, Naik G, Gilbert RE. Aliskiren, a novel renin inhibitor, is renoprotective in a model of advanced diabetic nephropathy in rats. Diabetologia. 2007;50(11):2398‐2404. - PubMed
    1. Ichihara A, Sakoda M, Kurauchi‐Mito A, et al. New approaches to blockade of the renin‐angiotensin‐aldosterone system: characteristics and usefulness of the direct renin inhibitor Aliskiren. J Pharmacol Sci. 2010;113(4):296‐300. - PubMed
    1. Persson F, Rossing P, Schjoedt KJ, et al. Time course of the antiproteinuric and antihypertensive effects of direct renin inhibition in type 2 diabetes. Kidney Int. 2008;73(12):1419‐1425. - PubMed