Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2019 May;15(5):253-254.
doi: 10.1038/s41584-019-0204-z.

Cholesterol and cartilage do not mix well

Frank Beier  1
Affiliations
Comment

Cholesterol and cartilage do not mix well

Frank Beier. Nat Rev Rheumatol. 2019 May.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Zai, G. Alteration of metabolic pathways in osteoarthritis. Metabolites 9, 11 (2019). - DOI
    1. Choi, W. S. et al. The CH25H–CYP7B1–RORα axis of cholesterol metabolism regulates osteoarthritis. Nature 566, 254–258 (2019). - DOI
    1. Sun, M. M., Beier, F. & Ratneswaran, A. Nuclear receptors as emerging drug targets in osteoarthritis. Curr. Opin. Pharmacol. 40, 81–86 (2018). - DOI
    1. Ali, S. A. et al. Regulation of cholesterol homeostasis by Hedgehog signaling in osteoarthritic cartilage. Arthritis Rheumatol. 68, 127–137 (2016). - DOI
    1. Farnaghi, S. et al. Cholesterol metabolism in pathogenesis of osteoarthritis disease. Int. J. Rheum. Dis. 20, 127–130 (2017). - DOI

LinkOut - more resources