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. 2020 Jan;27(1):125-139.
doi: 10.1080/13825585.2019.1597008. Epub 2019 Mar 27.

The relationship of longitudinal cognitive change to self-reported IADL in a general population

Jesse S Passler  1 , Richard E Kennedy  2 , Olivio J Clay  1 , Michael Crowe  1 , Virginia J Howard  3 , Mary Cushman  4 , Frederick W Unverzagt  5 , Virginia G Wadley  2
Affiliations

The relationship of longitudinal cognitive change to self-reported IADL in a general population

Jesse S Passler et al. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 2020 Jan.

Abstract

This study examined the relationship between cognitive change and instrumental activities of daily living (IADL) in a large, national, population-based sample. Cognitive change was assessed via verbal fluency, word list learning (WLL), and word list delayed recall (WLD). Incident cognitive impairment was defined by change in Six-Item Screener (SIS) status over a period of 10 years. Impaired IADL was defined as self-reported difficulty or needing assistance performing any IADL at Year 10. A one-word decrease in WLL over a 10-year span increased the odds of impaired IADL by 16% (95% CI 1.08-1.24) and incident cognitive impairment increased the odds of impaired IADL by 59% (95% CI 1.36-1.85) when adjusting for demographic factors, health-related behaviors, vascular risk factors and disease, and depressive symptoms. Cognitive change most strongly predicted impairment in managing finances (OR 2.47, 95% CI 2.04-3.00) and driving (OR 2.06, 95% CI 1.73-2.44).

Keywords: Cognitive aging; depression; instrumental activities of daily living; longitudinal studies; stroke.

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Conflict of interest statement

Conflicts of Interest: The authors report no financial, personal, or potential conflicts of interest.

Figures

Figure 1 -
Figure 1 -. Participant Cohorts
A visualization of participant cohorts for the present study analysis, as derived from the total REasons for Geographic and Racial Differences in Stroke (REAGRDS) sample. Sample sizes are displayed by exclusion criteria for respective predictors of interest (i.e., incident cognitive impairment and cognitive change slopes).
See this image and copyright information in PMC

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