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. 2019 Mar 10:27:e3126.
doi: 10.1590/1518-8345.2959.3126.

Acupuncture in adults with Chemotherapy-Induced Peripheral Neuropathy: a systematic review

[Article in English, Portuguese, Spanish]
Amanda Fonseca Baviera  1 , Karin Olson  2 , Juliana Maria de Paula  1 , Bruna Francielle Toneti  1 , Namie Okino Sawada  1
Affiliations

Acupuncture in adults with Chemotherapy-Induced Peripheral Neuropathy: a systematic review

[Article in English, Portuguese, Spanish]
Amanda Fonseca Baviera et al. Rev Lat Am Enfermagem. .

Abstract
in English, Portuguese, Spanish

Objective: to analyze and synthesize knowledge about the effect of acupuncture on chemotherapy-induced peripheral neuropathy symptoms in adults with cancer.

Method: the method used was a Systematic Review. Potential articles were identified by searching in the PubMed of National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, Embase, Cochrane Central and Scopus. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses strategy, 607 articles were identified. After removing the duplicates, all titles and abstracts were reviewed, and seven articles were selected for full review. After the full review, five studies were selected for inclusion.

Results: of the five articles included, four were cohort studies and one was a quasi-experimental study. All articles showed that acupuncture was associated with an improvement in the peripheral neuropathy, but the type of protocol, use of medications, time of treatment, and different outcome measures made it difficult to compare the studies.

Conclusion: the use of acupuncture appears to be associated with an improvement in the symptoms of chemotherapy-induced peripheral neuropathy and has no side effects. In order to improve the evidence about benefits associated with acupuncture, more experimental studies using both subjective and objective measures are needed.

Objetivo:: analisar e sintetizar o conhecimento sobre o efeito da acupuntura nos sintomas da neuropatia periférica induzida por quimioterapia em adultos com câncer.

Método:: o método utilizado foi uma Revisão Sistemática. Artigos potenciais foram identificados através de pesquisa na PubMed of National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, Embase, Cochrane Central e Scopus. Seguindo a estratégia Preferred Reporting Items for Systematic Reviews and Meta-Analysis foram identificados 607 artigos. Depois de eliminar artigos duplicados, todos os títulos e resumos foram revisados, deixando sete artigos para revisão na íntegra, e após tal revisão, cinco artigos foram selecionados para inclusão no presente estudo.

Resultados:: dos cinco artigos incluídos, quatro eram estudos de coorte e um era um estudo quase experimental. Todos os artigos mostraram que a acupuntura estava associada a uma melhora na neuropatia periférica, mas o tipo de protocolo, o uso de medicamentos, o tempo de tratamento e as diferenças entre as medidas de desfecho dificultaram a comparação entre os estudos.

Conclusão:: o uso da acupuntura parece estar associado à melhora dos sintomas da neuropatia periférica induzida por quimioterapia e não tem efeitos colaterais. São necessários mais estudos experimentais usando tanto medidas subjetivas como objetivas para melhorar as evidências sobre os benefícios associados à acupuntura.

Objetivo:: analizar y sintetizar el conocimiento sobre el efecto de la acupuntura en los síntomas de neuropatía periférica inducida por quimioterapia en los adultos con cáncer.

Método:: el método utilizado fue una Revisión Sistemática. Artículos potenciales se identificaron mediante la búsqueda en PubMed of National Library of Medicine, Cumulative Index to Nursing and Allied Health Literature, Embase, Cochrane Central y Scopus. Siguiendo los elementos de informes Preferred Reporting Items for Systematic Reviews and Meta-Analyses, se identificaron 607 artículos. Después de eliminar los duplicados, se revisaron todos los títulos y resúmenes, quedando siete artículos para una revisión completa y después de la revisión completa, se seleccionaron cinco estudios para su inclusión.

Resultados:: de los cinco artículos incluidos, cuatro fueron estudios de cohortes y uno fue un estudio cuasi experimental. Todos los artículos mostraron que la acupuntura se asoció con una mejoría en la neuropatía periférica, pero el tipo de protocolo, el uso de medicamentos, el tiempo de tratamiento y las diferencias entre las medidas de resultado dificultaron la comparación de los estudios.

Conclusión:: el uso de la acupuntura parece estar asociado con una mejoría en los síntomas de la neuropatía periférica inducida por quimioterapia y sin efectos secundarios. Para mejorar la evidencia sobre los beneficios asociados con la acupuntura, se necesitan más estudios experimentales que utilicen medidas subjetivas y objetivas.

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Figures

Figure 1
Figure 1. Flowchart, according to PRISMA*, to select the studies found
Figure 2
Figure 2. Evaluation of the methodological quality of the quasi-experimental study included in the review according Joanna Briggs Institute Critical Appraisal Tools
Figure 3
Figure 3. Evaluation of the methodological quality of the cohort studies included in the review according Joanna Briggs Institute Critical Appraisal Tools
Figure 4
Figure 4. Summary of studies on acupuncture intervention
See this image and copyright information in PMC

References

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