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Review
. 2019 Jan-Dec:24:2515690X19834169.
doi: 10.1177/2515690X19834169.

Complementary Therapies as a Strategy to Reduce Stress and Stimulate Immunity of Women With Breast Cancer

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Review

Complementary Therapies as a Strategy to Reduce Stress and Stimulate Immunity of Women With Breast Cancer

Camila Aparecida Abrahão et al. J Evid Based Integr Med. 2019 Jan-Dec.

Abstract

The stress associated with cancer development leads to disturbances in the hypothalamic-pituitary-adrenal axis and suppresses important facets of the immune response. The use of complementary therapies in the treatment of women with breast cancer has demonstrated therapeutic benefits that entail improvements in the patients' quality of life. The objective of this article is to present evidence on the use of complementary therapies as a stress reduction strategy and on its stimulating effects on the immune system of women with breast cancer. This is a reflexive updating article that will support the health professionals' understanding on the use of complementary therapies in breast cancer care. The use of complementary therapies in the treatment of women with breast cancer has significantly improved these subjects' stress, depression, fatigue, anxiety, and, consequently, their quality of life, as well as their immune response, which is mainly illustrated by the increased number and cytotoxic activity of natural killer cells. Clinicians, health professionals, and patients need to be cautious about using complementary therapies and fully understand the real benefits and risks associated with each therapy. Little or no supporting evidence is available to clarify the effects on the immune system of women with breast cancer, and the consequent therapeutic benefits obtained through the use of these practices.

Keywords: breast cancer; complementary therapies; immune system; physiological stress.

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Conflict of interest statement

Declaration of Conflicting Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

References

    1. Hamer J, McDonald R, Zhang L, et al. Quality of life (QOL) and symptom burden (SB) in patients with breast cancer. Support Care Cancer. 2017;25:409–419. - PubMed
    1. Bouskill K, Kramer M. The impact of cancer and quality of life among long-term survivors of breast cancer in Austria. Support Care Cancer. 2016;24:4705–4712. - PubMed
    1. Chandwani KD, Ryan JL, Peppone LJ, et al. Cancer-related stress and complementary and alternative medicine: a review. Evid Based Complement Alternat Med. 2012;2012:979213. - PMC - PubMed
    1. Kang E, Yang EJ, Kim SM, et al. Complementary and alternative medicine use and assessment of quality of life in Korean breast cancer patients: a descriptive study. Support Care Cancer. 2012;20:461–473. - PubMed
    1. Chiriac VF, Baban A, Dumitrascu DL. Psychological stress and breast cancer incidence: a systematic review. Clujul Med. 2018;91:18–26. doi:10.15386/cjmed-924 - PMC - PubMed

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